Table 3.

Functional activations for Funny > Positive contrast, with age as a covariate of interest

LocationAnatomical locationTalairach (peak) coordinateCluster size (voxel)z scorePeak voxel p value
xyz
BA 44Right inferior frontal gyrus5310122474.41<0.0005
BA 2Right postcentral gyrus57−20291194.06<0.0005
PutamenRight nucleus accumbens (putamen)169−121684.01<0.0005
BA 19Right lingual gyrus24−64−2823.78<0.0005
Midline midbrain (substantia nigra and red nucleus)14−12−133133.76<0.0005
BA 21Right temporal lobe40−3−12783.49<0.0005
  • These activations represent negative correlations—that is, greater activity for younger participants. Activation maps are presented with a peak-level threshold of p < 0.001 uncorrected, with a cluster (extent) threshold of 30 voxels.