Table 2.

Comparison of neuromuscular junctions by genotype

Type of NMJNumber of NMJsActive zone length (nm)Vesicles per active zoneSynapse length (nm)aVesicles per profile
Wild typeGABAergic11122.7 ± 15.040.7 ± 2.71006.2 ± 77.526.1 ± 0.9
fmi-1(ju43)GABAergic375.0 ± 15.060.7 ± 11.8465.0 ± 150.0*23.4 ± 7.2
fmi-1(ju58)GABAergic6120.0 ± 19.021.5 ± 2.6*472.5 ± 25.3*16.6 ± 1.3*
wild typeCholinergic23184.0 ± 14.126.5 ± 2.8637.8 ± 56.420.4 ± 1.9
fmi-1(ju43)Cholinergic19165.8 ± 23.121.4 ± 1.1746.1 ± 67.021.4 ± 1.1
fmi-1(ju58)Cholinergic21182.1 ± 24.027.8 ± 2.5615.0 ± 55.522.2 ± 1.9
  • aDefined as consecutive sections with synaptic vesicles.

  • *p < 0.01, significantly different from wild type.