Table 1.

Homer1c values during BDNF-induced plasticity

Brain regionExperimentTreatmentΔCTStatistics
Hippocampus78DHF78DHF10.89p = 0.70
Control11.21
Actinomycin D (ActD)BDNF12.44BDNF: F(1,20) = 1.09
BDNF + ActD13.43ActD: F(1,20) = 0.083
ActD13.26BDNF × ActD: F(1,20) = 0.22
Control12.93
U0126BDNF11.99BDNF: F(1,20) = 0.13
BDNF + U012615.87U0126: F(1,20) = 0.065
U012615.94BDNF × U0126: F(1,20) = 0.0031
Control15.72
ERKBDNF−5.383BDNF: F(1,20) = 11.13
BDNF + ERK −/−−1.91ERK: F(1,20) = 16.94
ERK −/−−1.52BDNF × ERK: F(1,20) = 0.087
WT7.87
Amygdala78DHF78DHF11.08p < 0.05
Control13.82
Actinomycin DBDNF11.26BDNF: F(1,20) = 0.99
BDNF + ActD12.16ActD: F(1,20) = 2.83
ActD13.67BDNF × ActD: F(1,20) = 0.017
Control11.99
U0126BDNF12.79BDNF: F(1,20) = 0.25
BDNF + U012614.89U0126: F(1,20) = 0.13
U012616.94BDNF × U0126: F(1,20) = 0.093
Control15.60
ERKBDNF−4.35BDNF: F(1,20) = 0.018
BDNF + ERK −/−−1.54ERK: F(1,20) = 0.43
ERK −/−−3.81BDNF × ERK: F(1,20) = 0.096
WT−1.92