Table 1.

Calculated (with STANPUMP software) and measured drug concentrations in plasma during the neuroimaging sessions

DrugSedLOCROCLOC-2
CalculatedMeasuredCalculatedMeasuredCalculatedMeasuredCalculatedMeasured
Dexmedetomidine (ng/ml)1.7 ± 0.42.3 ± 0.72.1 ± 0.63.2 ± 1.32.1 ± 0.63.0 ± 1.12.1 ± 0.72.8 ± 1.1
Propofol (μg/ml)1.6 ± 0.51.3 ± 0.52.2 ± 0.61.8 ± 0.61.6 ± 0.50.6 ± 0.4NANA
  • Sed, sedation; LOC, loss of consciousness; ROC, return of consciousness; LOC-2, second loss of consciousness (dexmedetomidine only); NA = not applicable. Data as mean ± SD.