Transgenic mice were used to assess the roles of BDNF in axon regeneration
| Genotype | Treatment tamoxifen (Tx) or saline (UT) | Host mouse or nerve donor | BDNF alleles |
|---|---|---|---|
| WT, tomato | Tx or UT | Donor | Systemic BDNF +/+ |
| thy-1-YFP-H | UT | Host | Systemic BDNF +/+ |
| Tam-Cre::BDNFf/f | Tx | Donor | Systemic BDNF −/− |
| Tam-Cre::BDNFf/f | UT | Donor | Systemic BDNF +/+ |
| Tam-Cre::BDNFf/w | Tx | Donor | Systemic BDNF +/− |
| Tam-Cre::BDNFf/w | UT | Donor | Systemic BDNF +/+ |
| CNTF-Cre::BDNFf/f | UT | Donor | CNTF+ cells BDNF −/−, other cells BDNF+/+ |
| CNTF-Cre::BDNFf/w | UT | Donor | CNTF+ cells BDNF +/−, other cells BDNF+/+ |
| SLICK::BDNFf/f | Tx | Host | YFP+ neurons BDNF −/−, other cells BDNF +/+ |
| SLICK::BDNFf/w | Tx | Host | YFP+ neurons BDNF +/−, other cells BDNF +/+ |