Locales within regions hypothesized a priori (PFC and medial temporal cortex) in which resting rCBF was higher in women than in men
| Brain region | MNI coordinates | Cluster size | Z values | p values | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| R hippocampus | 22 | −30 | −2 | 16822 | 5.66 | 0.000000007* |
| L parahippocampal gyrus (BA36) | −38 | 4 | −32 | 209 | 4.56 | 0.000003* |
| R parahippocampal gyrus (BA36) | 32 | 8 | −38 | 254 | 4.08 | 0.00002 |
| L superior frontal gyrus (BA10) | −16 | 52 | −4 | 453 | 4.47 | 0.000004* |
| L superior frontal gyrus (BA8) | −38 | 26 | 46 | 123 | 4.24 | 0.00001 |
| R superior frontal gyrus (BA10) | 16 | 58 | −6 | 2724 | 4.06 | 0.00002 |
| R middle frontal gyrus (BA10) | 50 | 12 | 50 | 216 | 4.33 | 0.000008 |
| R middle frontal gyrus (BA10) | 40 | 52 | 22 | 2724 | 3.98 | 0.00003 |
| L middle frontal gyrus (BA10) | −34 | 60 | 6 | 453 | 3.89 | 0.00005 |
| L middle frontal gyrus (BA6) | −36 | 4 | 58 | 74 | 3.53 | 0.0002 |
| R inferior prefrontal gyrus (BA47) | 34 | 46 | −2 | 2724 | 4.20 | 0.00001 |
| L inferior prefrontal gyrus (BA47) | −52 | 24 | −8 | 10 | 3.33 | 0.0004 |
| R orbital frontal gyrus (BA11) | 40 | 58 | −10 | 2724 | 4.05 | 0.00003 |
| R DLPFC (BA46) | 52 | 30 | 30 | 77 | 4.04 | 0.00003 |
| L DLPFC (BA9) | −4 | 58 | 34 | 2724 | 3.77 | 0.00008 |
| Dorsal anterior cingulate (BA32) | 0 | 26 | 32 | 2724 | 3.90 | 0.00005 |
No regions showed the opposite effect.
↵* FWE corrected at p < 0.05. Cluster size reported at p < 0.001. Additional regions, including thalamus, right putamen, right postcentral gyrus, left cerebellum, bilateral superior temporal gyrus, angular gyrus, supramarginal gyrus, and visual association cortex, also showed higher rCBF for women than men at p ≤ 0.0006, uncorrected. L, Left; R, right.