Table 1.

EC50 and Hill coefficients obtained by two-electrode voltage clamp when untagged or VFP-tagged GlyR α− and β-subunits were expressed in Xenopus oocytes

Subunit compositionEC50m)Hill coefficientN (oocytes)
GlyRα303.8 ± 20.41.28 ± 0.095
GlyRα-FP266.2 ± 27.41.1 ± 0.14
GlyRα; GlyRβ357.9 ± 22.51.5 ± 0.15
GlyRα-FP; GlyRβ473.7 ± 24.31.5 ± 0.15
GlyRα; GlyRβ-FP408.5 ± 22.21.5 ± 0.16
GlyRα-FP; GlyRβ-FP331.1 ± 15.61.54 ± 0.096
  • Values are mean ± SEM.