Protein | Tryptic peptides derived from high-molecular-weight complex components |
---|---|
Fibronectin | K108VGDTYERPKD, R133ISCTIANRC, R567TFYQIGDSWEKF |
R584YQCYCYGRG, K1115LGVRPSQGGEAPRE, R1196STTPDITGYRI R1569ITYGETGGNSPVQEFTVPGSKS, K2349IGEKWDRQ | |
Vitronectin | K193LIQDVWGIEGPIDAAFTRI |
Neuregulin-1 | R79RNKPQNVKI |
Alpha-2-macroglobulin | R75RGNQSLFTDLVVDKD, K1018HRDGSYSTFGDKPGRS R1121NALFCLDTAWKS |
Neuroserpin | R38RGTGEDENILFSPLSIALAMGMMELGAQGSTRK K191SQFRPENTRT |
The proteomics screen, using tryptic peptides recovered from the gel, identified candidate substrates and inhibitors of neuropsin in cultured hippocampal neurons.