Table 2.

Changes in average response during cognitive regulation

RegionBACluster sizeZ scorexyz
Regions overlapping with areas correlated with NATURAL bid
    DISTANCE > NATURAL
        No regions significant
    DISTANCE < NATURAL
        R Dorsolateral prefrontal cortex10/46413.06*423321
    INDULGE > NATURAL
        L Ventral anterior cingulate/ventromedial prefrontal cortex32333.71−339−12
    INDULGE < NATURAL
        R Dorsolateral prefrontal cortex10/46373.39512742
    INDULGE > DISTANCE
        R Dorsal anterior cingulate cortex32484.4302415
        L Ventral anterior cingulate/ventromedial prefrontal cortex32603.73036−6
    INDULGE < DISTANCE
        No regions significant
Regions outside of areas correlated with NATURAL bid
    DISTANCE > NATURAL
        R Superior medial frontal gyrus810235.7633948
        R Ventrolateral prefrontal cortex45/474764.974236−18
        L Ventrolateral prefrontal cortex45/475665.01−57249
        R Temporal pole21724.944812−42
        R Posterior parietal cortex402054.6563−5133
        L Posterior parietal cortex403304.57−57−5433
    DISTANCE < NATURAL
        L Posterior insula13533.99−36−1815
        R Postcentral gyrus2544.0557−3363
        L Posterior cingulate29864.09−12−5715
    INDULGE > NATURAL
        R Superior frontal gyrus84004.6595136
        R Ventrolateral prefrontal cortex453444.603024−24
        L Ventrolateral prefrontal cortex452714.35−3312−15
        L Posterior parietal cortex40954.42−48−5427
        L Supplementary motor area6824.79−61563
        R Temporal pole21484.12456−36
    INDULGE < NATURAL
        L Occipital cortex19873.83−3−9318
    INDULGE > DISTANCE
        No regions significant
    INDULGE < DISTANCE
        No regions significant
Conjunction of regions in DISTANCE > NATURAL and INDULGE > NATURAL
    L Supplementary motor area6392−31563
    L Ventrolateral prefrontal cortex45219−2718−24
    R Ventrolateral prefrontal cortex4522757159
    L Superior frontal gyrus813−184536
    L Posterior parietal cortex4044−66−4836
  • Note: Clusters are reported at p < 0.05, whole-brain cluster corrected (p < 0.001, uncorrected, and minimum extent k = 44 voxels) unless otherwise noted. Clusters for conjunction are reported if they passed a voxel threshold of p < 0.05, WBC, for the contrast of DISTANCE > NATURAL and INDULGE > NATURAL, with a minimum overlap of >5 voxels. For ease of interpretation, the table is divided into (1) significant regions that overlapped with value-related areas (i.e., overlap with a mask including all voxels correlated with value during NATURAL trials at p < 0.001, uncorrected) and (2) regions with no overlap of value-related regions (i.e., overlap with a mask that excluded all voxels correlated with value during NATURAL trials at p < 0.001, uncorrected).

  • *p < 0.05, small-volume corrected within an anatomically defined mask including vmPFC, right dlPFC, and left dlPFC.

  • p < 0.005, uncorrected, reported for completeness.