Table 1.

Quantification of Fos expression in selected brain regions in Null vs Wt mice

Male WtMale Null
Medullan = 7n = 7
    Medial nTS106.5 ± 0.5326.4 ± 0.9***
    Lateral nTS137.9 ± 0.7447.9 ± 2.0***
    Commissural nTS21.8 ± 0.253.4 ± 0.5*
    Nucleus retroambiguus7.9 ± 1.211.9 ± 2.2#
    preBotzinger Complex23.6 ± 7.429.1 ± 4.7
Ponsn = 5n = 5
    Pontine nucleus322.7 ± 63.7199.4 ± 51.5
Midbrainn = 5n = 5
    Dorsal PAG21.6 ± 32.813.9 ± 4.7
    Lateral PAG53.0 ± 25.235.9 ± 10.7#
    Ventral PAG39.7 ± 12.325.6 ± 7.5*
Forebrainn = 5n = 5
    Piriform cortex266.3 ± 35.0124.2 ± 19.7*
    Nucleus accumbens114.4 ± 22.826.8 ± 7.9**
    Cingulate cortex50.4 ± 13.0814.8 ± 4.8*
    Retrosplenial cortex39.7 ± 10.867.4 ± 1.6*
    Prelimbic cortex34.6 ± 6.818.4 ± 3.6**
    Infralimbic cortex26.6 ± 3.87.0 ± 2.2**
    Motor cortex19.9 ± 3.83.1 ± 1.6**
    Lateral septal nucleus48.6 ± 14.911.6 ± 4.9*
    Hippocampus (CA1 + CA3)22.5 ± 8.314.0 ± 4.6
    Hippocampus (DG)14.3 ± 4.79.5 ± 2.6
  • Data are displayed as mean ± SEM (*p < 0.05; **p < 0.01; ***p < 0.001;

  • #p < 0.15).