Quantification of AP and inward current changes during DP block development
| AP position | AP peak (mV) | AP AHP (mV) | AP threshold (mV) | Peak AIS dV/dt (V/s) | Peak somatic dV/dt (V/s) | |
|---|---|---|---|---|---|---|
| Current | 1st | 26.5 ± 1.4 | −56.5 ± 1.3 | −40.8 ± 1.8 | 59.4 ± 5.8 | 125.7 ± 9.0 |
| n = 9 | 4th | 47.3 ± 4.4 | 73.6 ± 5.9 | |||
| Last | 13.8 ± 3.3 | −48.9 ± 1.1 | −31.5 ± 1.7 | 33.2 ± 5.4 | 46.9 ± 7.3 | |
| gNMDA | 1st | 28.0 ± 1.4 | −60.2 ± 1.8 | −41.4 ± 1.2 | 65.2 ± 5.0 | 141.3 ± 12.1 |
| n = 7 | 1 s | 41.4 ± 4.5 | 61.7 ± 8.8 | |||
| 2 s | 30.4 ± 2.7 | 38.3 ± 5.3 | ||||
| Last | 11.8 ± 2.7 | −53.8 ± 2.7 | −26.7 ± 1.4 | 26.9 ± 3.7 | 32.8 ± 9.4 |