Analysis/brain region | Hemisphere | k | MNI coordinates | ||
---|---|---|---|---|---|
x | y | z | |||
Amnesic patients < Controls | |||||
Default network regions | |||||
Hippocampus | R | 118 | 32 | −20 | −16 |
Parahippocampal cortex | L | 57 | −26 | −38 | −12 |
Thalamus | L | 69 | −22 | −32 | −2 |
Precuneus | L | 680 | −12 | −66 | 38 |
Cuneus | L | −22 | −78 | 24 | |
Precuneus | L | 101 | −6 | −46 | 40 |
Superior frontal gyrus | R | 26 | 6 | 62 | 22 |
Putamen | R | 16 | 22 | 4 | −12 |
Regions outside of default network | |||||
Supramarginal gyrus | R | 101 | 62 | −30 | 30 |
Superior parietal lobule/angular gyrus | R | 68 | 36 | −54 | 50 |
Pars opercularis | R | 88 | 60 | 12 | 12 |
Pars triangularis | R | 25 | 38 | 34 | 4 |
Rostral middle frontal gyrus | R | 64 | 42 | 34 | 36 |
Rostral middle frontal gyrus | R | 39 | 38 | 38 | 12 |
Caudal anterior cingulate | R | 58 | 8 | 18 | 24 |
Lateral orbitofrontal cortex | R | 17 | 38 | 26 | −14 |
Insula | L | 19 | −34 | 14 | 0 |
Amygdala | R | 37 | 30 | 0 | −16 |
Occipital pole | L | 503 | −20 | −102 | −6 |
Occipital pole | R | 244 | 20 | −100 | 4 |
Lateral occipital cortex | R | 106 | 32 | −82 | 16 |
Precentral gyrus | R | 362 | 50 | −6 | 48 |
Precentral gyrus | L | 93 | −56 | 6 | 14 |
Precentral gyrus | L | 54 | −30 | −24 | 56 |
Amnesic patients > Controls | |||||
Default network regions | |||||
Rostral anterior cingulate/vmPFC | R | 881 | 6 | 26 | −14 |
Rostral anterior cingulate/amPFC | R | 6 | 50 | 0 | |
Rostral anterior cingulate/vmPFC | L | −4 | 26 | 18 | |
Rostral anterior cingulate/amPFC | L | −4 | 48 | −2 | |
Medial frontal gyrus/DMPFC | L | −6 | 60 | 12 | |
Medial frontal gyrus | L | 17 | −4 | 66 | 4 |
Superior frontal gyrus | L | 214 | −6 | 48 | 36 |
Superior frontal gyrus | R | 49 | 12 | 46 | 36 |
Middle/superior frontal gyrus | L | 36 | −24 | 18 | 38 |
Posterior cingulate cortex | L | 740 | −8 | −54 | 24 |
Posterior cingulate cortex | R | 6 | −46 | 22 | |
Retrosplenial cortex | L | −18 | −54 | 6 | |
Posterior inferior parietal lobe | L | 318 | −46 | −72 | 36 |
Posterior inferior parietal lobe | L | 129 | −32 | −76 | 36 |
Posterior inferior parietal lobe | R | 41 | 36 | −74 | 48 |
Posterior inferior parietal lobe | R | 57 | 46 | −74 | 30 |
Angular gyrus | R | 235 | 44 | −54 | 16 |
Middle/inferior temporal gyrus | R | 127 | 56 | −6 | −30 |
Regions outside of default network | |||||
Medial frontal gyrus | L | 17 | −6 | 12 | 60 |
Medial frontal gyrus | L | 108 | −12 | 22 | 52 |
Rostral middle frontal gyrus | R | 103 | 42 | 4 | 36 |
Posterior superior frontal gyrus | R | 46 | 22 | 10 | 48 |
Supramarginal gyrus | R | 35 | 46 | −40 | 26 |
Precuneus | R | 27 | 6 | −54 | 60 |
Banks of superior temporal sulcus | L | 85 | −46 | −52 | 4 |
Inferior temporal gyrus | L | 19 | −58 | −60 | −14 |
Lingual gyrus | L | 55 | −8 | −78 | −12 |
Changes that occurred within the group PCC connectivity map were considered to be within the DN, whereas changes outside of the map were classified as regions outside of the DN. L, Left; R, right; k, voxel extent; amPFC, anterior medial prefrontal cortex; vmPFC, ventromedial prefrontal cortex.