Expression levels of MMP-related genes in the normal cochlear sensory epithelium (ΔCt values for the reference genes)
| Gene | Apical samples ΔCt (mean ± SD) | Basal samples ΔCt (mean ± SD) |
|---|---|---|
| Timp3 | 0.8 ± 0.4 | 0.2 ± 0.3 |
| Timp2 | 3.6 ± 1.5 | 5.8 ± 0.3 |
| Mmp11 | 3.7 ± 0.3 | 5.2 ± 0.1 |
| Adamts1 | 4.5 ± 0.4 | 4.2 ± 0.5 |
| Mmp2 | 5.7 ± 1.0 | 8.4 ± 0.1 |
| Mmp14 | 5.8 ± 1.5 | 9.8 ± 0.4 |
| Mmp15 | 6.6 ± 1.9 | 10.0 ± 0.5 |
| Mmp16 | 6.8 ± 0.4 | 8.6 ± 0.4 |
| Timp1 | 7.2 ± 1.4 | 10.2 ± 0.4 |
| Adamts2 | 7.3 ± 1.8 | 12.5 ± 0.7 |
| Adamts5 | 7.6 ± 1.6 | 11.6 ± 0.8 |
| Mmp13 | 10.0 ± 1.6 | 16.0 ± 2.5 |
| Mmp12 | 10.5 ± 2.9 | 11.3 ± 1.5 |
| Mmp9 | 11.2 ± 2.2 | 16.2 ± 0.4 |
| Mmp10 | 13.1 ± 0.3 | 16.7 ± 1.0 |
| Mmp8 | 13.3 ± 5.1 | 15.1 ± 1.5 |
| Adamts8 | 13.6 ± 1.7 | 16.4 ± 0.4 |
| Mmp1a | 15.2 ± 1.2 | 16.6 ± 0.6 |
| Mmp3 | 15.4 ± 2.5 | 16.8 ± 1.1 |
| Mmp7 | Undetectable | Undetectable |
Data are means ± SD from four biological repeats, and are ranked in the order of abundance from highest to lowest.