Contrast-induced rate modulation (quantified by MIs) for different analysis time windows (relative to response onset) and for control and drug-applied conditions
| Drug condition | Analysis window | Contrast MI (median/interquartile range) | Significance (MI group difference) |
|---|---|---|---|
| ACh not applied | 0–150 ms | 0.249/0.265 | p = 0.797 |
| ACh applied | 0–150 ms | 0.276/0.269 | |
| ACh not applied | 150–550 ms | 0.183/0.218 | p = 0.635 |
| ACh applied | 150–550 ms | 0.145/0.312 | |
| Gabazine not applied | 0–150 ms | 0.223/0.308 | p = 0.644 |
| Gabazine applied | 0–150 ms | 0.217/0.377 | |
| Gabazine not applied | 150–550 ms | 0.187/0.235 | p = 0.284 |
| Gabazine applied | 150–550 ms | 0.145/0.309 |
Positive values indicate higher discharge rates when high-contrast stimuli (25%) were presented. p values indicate whether the respective MI distributions were significantly different (rank-sum test).