Electrophysiological and synaptic properties of granule cells
| RhebCA (mean ± SEM) | n | CTRL | n | % change (Rheb/CTRL) | p | |
|---|---|---|---|---|---|---|
| Resting potential (mV) | −57.2 ± 3.5 mV | 8 | −40.3 ± 3.9 | 7 | 29.5 | 0.001 |
| Rm (GΩ) | 1.5 ± 0.3 | 6 | 3.5 ± 0.6 | 5 | 43.9 | 0.05 |
| Cm (GΩ) | 13.6 ± 2.4 | 6 | 9.7 ± 0.7 | 5 | 40.3 | NS |
| IEI (ms) | 90.9 ± 2.4 | 8 | 780.7 ± 32.9 | 8 | 89 | 0.001 |
| AP threshold (mV) | −53.6 ± 2.5 | 6 | −49.9 ± 5.9 | 5 | 7.5 | NS |
| AP width (ms) | 1.5 ± 0.2 | 8 | 3.0 ± 0.7 | 7 | 50 | NS |
| AP amplitude (mV) | 81.2 ± 4.8 | 8 | 68.4 ± 7.3 | 7 | 18.7 | NS |
| AP number | 6.0 ± 2.0 | 8 | 6.6 ± 1.1 | 7 | 7.5 | NS |
CTRL, Control; IEI, interevent interval; AP, action potential; NS, not significant.