Expressed constructs | V_{1/2} (mV)^{a} | Slope (zF/RT)^{a} | Activation constant (ms)^{b} | Deactivation constant (ms)^{c} |
---|---|---|---|---|

X. laevis oocytes | ||||

Kv7.2/3 | −31.6 ± 0.6 (n = 57) | 8.8 ± 0.3 (n = 57) | 102.8 ± 12.2 (n = 11) | 55.3 ± 3.5 (n = 10) |

Kv7.2/3 + SGK1.1 | −31.1 ± 0.6 (n = 60) | 9 ± 0.3 (n = 60) | 140.4 ± 25.7 (n = 8) | 42.6 ± 5.9 (n = 4) |

HEK293 | ||||

Kv7.2/3 | −21.27 ± 1.8 (n = 11) | 13.8 ± 1.3 (n = 11) | 80.4 ± 13.5 (n = 11) | 43.3 ± 10.1 (n = 10) |

Kv7.2/3 + SGK1.1 | −19.43 ± 1.2 (n = 14) | 14.98 ± 0.5 (n = 14) | 72.3 ± 8.7 (n = 14) | 49.2 ± 6.4 (n = 12) |

↵

Half-maximal activation voltage calculated from Boltzmann equation fits to activation curves (Fig. 1^{a}*B*,*E*).↵

Calculated from monoexponential fits to evoked currents at + 40 mV from −80 mV (oocytes) or −30 mV (HEK293).^{b}↵

Calculated from monoexponential fits to evoked currents at −100 mV from holding potentials of + 50 mV (oocytes) or −30 mV (HEK293).^{c}