Locations where SPM voxelwise correlations between MP-induced changes in BPND and changes in regional metabolism were significantly greater for alcoholics than controlsa
x | y | z | Controls (r) | Alcoholic (r) | F, p | |
---|---|---|---|---|---|---|
L ACC | −2 | 34 | 10 | 0.68 | 0.96 | 13, p < 0.0001 |
R ACC | 10 | 28 | 18 | 0.52 | 0.94 | 8, p < 0.001 |
R ACC | 8 | 36 | 20 | 0.46 | 0.93 | 9, p < 0.0001 |
Inferior frontal BA 45 | 48 | 24 | 10 | 0.43 | 0.87 | 9, p < 0.0001 |
Inferior frontal BA 45 | 40 | 30 | 4 | −0.07 | 0.75 | 12, p < 0.0001 |
SMA BA 6 | 10 | 0 | 54 | 0.31 | 0.76 | 8, p < 0.002 |
Superior medial Frontal | 6 | 52 | 38 | 0.07 | 0.81 | 11, p < 0.0001 |
8 | 58 | 32 | −0.06 | 0.85 | 13, p < 0.0001 | |
Middle OFC | 8 | 68 | −14 | 0.64 | 0.92 | 7, p < 0.004 |
Fusiform | 40 | −28 | −26 | 0.41 | 0.87 | 9, p < 0.0001 |
Lingual | 8 | −36 | −8 | 0.43 | 0.93 | 10, p < 0.0001 |
Parahippocampal | 30 | 0 | −32 | 0.01 | 0.95 | 10, p < 0.0001 |
Precuneus | 2 | −66 | 40 | −0.02 | 0.79 | 8, p < 0.002 |
↵aMNI coordinates (x, right left; y, anterior posterior; z, superior inferior), the correlation values (r) for the controls and the alcoholics, and the F values for the comparisons of the correlations and their significance level (p). None of the correlations in controls was greater than in alcoholics.
L, Left; R, right; SMA, supplementary motor area.