Table 6.

Locations where SPM voxelwise correlations between MP-induced changes in BPND and changes in regional metabolism were significantly greater for alcoholics than controlsa

xyzControls (r)Alcoholic (r)F, p
L ACC−234100.680.9613, p < 0.0001
R ACC1028180.520.948, p < 0.001
R ACC836200.460.939, p < 0.0001
Inferior frontal BA 454824100.430.879, p < 0.0001
Inferior frontal BA 4540304−0.070.7512, p < 0.0001
SMA BA 6100540.310.768, p < 0.002
Superior medial Frontal652380.070.8111, p < 0.0001
85832−0.060.8513, p < 0.0001
Middle OFC868−140.640.927, p < 0.004
Fusiform40−28−260.410.879, p < 0.0001
Lingual8−36−80.430.9310, p < 0.0001
Parahippocampal300−320.010.9510, p < 0.0001
Precuneus2−6640−0.020.798, p < 0.002
  • aMNI coordinates (x, right left; y, anterior posterior; z, superior inferior), the correlation values (r) for the controls and the alcoholics, and the F values for the comparisons of the correlations and their significance level (p). None of the correlations in controls was greater than in alcoholics.

  • L, Left; R, right; SMA, supplementary motor area.