Table 3.

Relative quantity (fold change from vehicle) of neuronal TRPV1 and TRPA1 gene transcripts in CP

DRGNG
TRPV1TRPA1TRPV1TRPA1
Caerulein
    3 weeks2.03 (48)*2.13 (49)*2.65 (33)*2.40 (34)*
    6 weeks2.62 (45)*2.58 (42)*3.08 (29)*3.32 (28)*
    10 weeks2.86 (44)*2.83 (40)*3.39 (30)*3.31 (29)*
Caerulein + TRPV1/TRPA1
    <3 weeks1.21 (42)†1.16 (41)†1.34 (28)†1.11 (31)†
    >3 weeks1.99 (40)*1.91 (43)*2.26 (32)*1.68 (26)*

  • The numbers of cells used for mRNA quantification are indicated in parentheses. Data were analyzed by one-way ANOVA.

  • ↵*p < 0.05 versus vehicle;

  • ↵†p < 0.05 versus caerulein for 6 weeks with a Holm-Sidak post hoc test to compare groups.