Summary of histological analysis
| Experimental group | Corrected p75NTR cell count (n = 12) | AChE fiber density (OF/μm3) (n = 6) | |||
|---|---|---|---|---|---|
| NB | Medial septum | PEG | MEG | AEG | |
| Controls | 1144 ± 253.6 | 3148 ± 730 | 0.840 ± 0.071 | 0.706 ± 0.067 | 0.669 ± 0.068 |
| Cholinergic lesions | 415 ± 432 | 2901 ± 477 | 0.761 ± 0.149 | 0.537 ± 0.177 | 0.568 ± 0.159 |
p75NTR-IR neurons were quantified in serial sections through the NB and the medial septum for each hemisphere, and neuron counts were corrected for tissue volume using a method described by Konigsmark et al. (1969). AChE fiber density was quantified separately in the middle (MEG), anterior (AEG), and posterior (PEG) regions of the ectosylvian gyrus. Values are means ± SD. PV-IR neurons in the NB were quantified in the same way as p75NTR-IR neurons (data not shown).