Table 2.

Statistical analysis of the performance of Stop-CB1, WT, and CB1-RS mice in fear extinction

Repeated-measures ANOVAFactorFpPost hoc Gp
For 20 s time bins
    d1G × TF(9.20,124.22) = 1.400.193Stop-CB1 vs WT0.033
TF(4.60,124.22) = 28.19<0.001Stop-CB1 vs CB1-RS0.005
GF(2,27) = 6.700.004WT vs CB1-RS1.000
    d2G × TF(11.42,154.15) = 1.760.062Stop-CB1 vs WT0.025
TF(5.71,154.15) = 16.55<0.001Stop-CB1 vs CB1-RS0.008
GF(2,27) = 6.410.005WT vs CB1-RS1.000
    d3G × TF(9.94,134.24) = 0.880.557Stop-CB1 vs WT0.008
TF(4.97,134.24) = 16.02<0.001Stop-CB1 vs CB1-RS0.137
GF(2,27) = 5.560.010WT vs CB1-RS0.723
    d10G × TF(8.39,113.27) = 0.760.642Stop-CB1 vs WT<0.001
TF(4.20,113.27) = 7.71<0.001Stop-CB1 vs CB1-RS0.027
GF(2,27) = 12.47<0.001WT vs CB1-RS0.120
For days
    Tone minus BaselineG × TF(6,81) = 1.410.220Stop-CB1 vs WT<0.001
TF(3,81) = 36.02<0.001Stop-CB1 vs CB1-RS0.003
GF(2,27) = 10.62<0.001WT vs CB1-RS1.000
    Initial 20 s minus BaselineG × TF(6,81) = 2.170.054Stop-CB1 vs WTnd
TF(3,81) = 23.83<0.001Stop-CB1 vs CB1-RSnd
GF(2,27) = 2.020.152WT vs CB1-RSnd
    BaselineG × TF(6,81) = 0.390.885Stop-CB1 vs WTnd
TF(3,81) = 47.60<0.001Stop-CB1 vs CB1-RSnd
GF(2,27) = 0.020.982WT vs CB1-RSnd
    After toneG × TF(6,81) = 0.300.937Stop-CB1 vs WT0.004
TF(3,81) = 8.65<0.001Stop-CB1 vs CB1-RS0.181
GF(2,27) = 6.520.005WT vs CB1-RS0.336
  • G, genotype; T, time; d, day; nd, not determined.