Table 4.

Cluster maxima for all other regions of statistically significant increased BOLD signal in emotionally salient conditions relative to neutral for controls and patients, aversive>neutral

Control groupPatient group
Aversive>neutralCluster sizep value**Peak voxelAversive>neutralCluster sizep valuePeak voxel
Brain regions (hemisphere)*t scorexyzBrain regions (hemisphere)t scorexyz
Midbrain (bilateral)763<0.00017.30−6−32−14Posterior thalamus (contralateral)960.0056.27−8−82
Amygdala (left)1040.0036.50−20−4−16Inferior frontal gyrus (contralateral)355<0.00015.61−481224
Posterior thalamus (left)193<0.00016.32−10−164Inferior parietal cortex (contralateral)445<0.00015.43−26−6042
Hippocampus (left)880.0056.04−24−32−6Inferior frontal gyrus (ipsilateral)1390.0015.31461228
Inferior frontal gyrus (right)428<0.00016.02561430Inferior frontal gyrus (contralateral)640.0274.84−4418−10
Posterior thalamus (right)154<0.00015.8210−1812Insula (contralateral)540.0434.54−38−2−6
Midbrain (left)870.0055.43−2−4−16Inferior frontal gyrus (contralateral)1000.0054.45−463018
Putamen (right)830.0065.4132−10−8
Caudate–putamen (left)1120.0025.04−84−2
Somatosensory cortex (left)263<0.00015.00−56−3030
Inferior frontal gyrus (left)1280.0014.87−44386
Caudate–putamen (left)1260.0014.84−16012
Postcentral gyrus (right)660.0154.5950−2642
Caudate–putamen (right)205<0.00014.5410212
Inferior frontal gyrus (left)510.0334.44−341024
Inferior parietal cortex (left)590.0214.41−38−4244
  • For patient contrasts, laterality is indicated in reference to lesion site.

  • *For brevity, submaxima are not reported but are available upon request.

  • **Topological FDR corrected value.