Table 5.

Cluster maxima for all other regions of statistically significant increased BOLD signal in emotionally salient conditions relative to neutral for controls and patients, erotic>neutral

Control groupPatient group
Erotic>neutralCluster sizep valuePeak voxelErotic>neutralCluster sizep valuePeak voxel
Brain regions (hemisphere)t scorexyzBrain regions (hemisphere)t scorexyz
Amygdala-hippocampus-midbrain (left)1079<0.00019.06−22−4−14Amygdalo-hippocampus-insular cortex (contralateral)2250<0.00017.26−32−16−4
Caudate–putamen (bilateral)968<0.00017.1618124Inferior frontal gyrus (contralateral)1171<0.00017.15−461024
Orbitofrontal (left)720.0116.68−2814−18Anterior cingulate cortex (bilateral)1315<0.00016.3804618
Anterior cingulate cortex (left)762<0.00016.43−10486Inferior frontal gyrus (ipsilateral)337<0.00015.98521034
Amygdala (right)880.0066.29284−20Brainstem900.0055.57−8−36−32
Cerebellar vermis (left)850.0066.19−2−58−34Posterior thalamus (ipsilateral)1110.0035.4812−2016
Premotor cortex (left)930.0055.76−54440Frontal eye fields (ipsilateral)670.0175.4330−246
Amygdala-hippocampus-midbrain (right)1420.0015.7518−8−10Midbrain (contralateral)1030.0035.24−4−30−4
Postcentral gyrus (right)1240.0015.6050−2642Amygdala-midbrain-thalamus (ipsilateral)1080.0035.2214−24−14
Precuneus (bilateral)217<0.00015.562−6040Middle and inferior frontal gyrus (contralateral)176<0.00014.92−343434
Inferior frontal gyrus (right)320<0.00015.3038630Orbitofrontal cortex (ipsilateral)570.0284.803230−18
Midbrain (bilateral)960.0055.15−6−34−26
Temporal pole (left)730.0114.78−4014−24
Middle frontal gyrus (left)590.0214.54−38386
  • For patient contrasts, laterality is indicated in reference to lesion site.