DRN GABA inhibition effects on anxiety-related behaviors: OFT
| Time in center of arena (s) | ||||
|---|---|---|---|---|
| GAD2-Cre/Arch | GAD2-Cre/tdTomato | |||
| Stim (±) | + | − | + | − |
| Defeated | 28.94 ± 7.19*** | 28.89 ± 6.61*** | 25.56 ± 7.38*** | 25.54 ± 9.34*** |
| Control | 56.09 ± 10.47 | 46.86 ± 8.59 | 50.50 ± 4.13 | 42.81 ± 8.79 |
Data are expressed as mean time in the center of arena ± SEM.
↵***Significant difference in defeated mice from undefeated controls of the same virus (GAD2-Cre/Arch or GAD2-Cre/tdTomato) and stimulation (+ or −) condition (p < 0.01, two-way ANOVA, Fisher's post hoc, control vs defeated).