Table 2.

Neural anticipation of losses and bidirectional responses

Cluster size (number of voxels)HemisphereAnatomical regionMNIT scoreCluster p value
xyz
Bidirectional response: activation for losses, deactivation for gains, correlation with loss aversion
    175RRolandic operculum/Insula (OP1)*58−20164.98<0.001
RSupramarginal gyrus (OP1)54−26183.17
Anticipation of losses
    1019LInsula (LG1/LG2)−38−2284.52<0.001
LInsula lobe (OP3)−36−14103.83
LRolandic operculum (OP1/OP2)−34−26163.43
    893RSuperior temporal gyrus42−1805.92<0.001
RAmygdala (CM/SF)/putamen282−105.15
RInsula lobe ((LG1/LG2/OP1)36−28183.37
    383LMiddle cingulate cortex−12−32484.510.032
RSMA8−28543.43
  • Asterisk indicates the region whose bidirectional response is depicted in Figure 3.