Table 3.

Numbers of D1R cells and D1R cells downregulated by chronic cocaine exposure

Animal IDNeurons in FOVDownregulated neurons in [Ca2+]iDownregulated neurons (%)
D1R neurons* (m = 3)
    S110770.00
    S2171694.12
    S3231565.22
        Mean ± SD17 ± 613 ± 576.45 ± 15.49
D2R neurons† (m = 4)
    S1141392.86
    S2181055.56
    S3141285.71
    S4171164.71
        Mean ± SD16 ± 212 ± 174.71 ± 17.49

  • ↵*D1R neuron with 50% lower Δ[Ca2+]i response to cocaine than that in naive mice.

  • ↵†D2R neuron with 50% lower Δ[Ca2+]i response to cocaine than that in naive mice.