Table 1.

Seizure-spread properties in the pilocarpine rat model versus patients

Pilocarpine rat model (in seconds)TLE patients (in seconds)
Average seizure duration40–90a,b,c110–120d,e,f,g
Average latency from electrographic to behavioral seizure onset∼5a16–19h,i
Average spread time to contralateral hemisphere∼2a20–30i,j,k
Average spread time across brain regions∼7a17–30d,e,h,i,l
  • Entries represent approximate average value (for single study) or range of average values across studies. For detailed references, see: aToyoda et al. 2013;

  • bLévesque et al., 2012;

  • cEnglot et al., 2008;

  • dBrekelmans, 1995;

  • eSpencer et al., 1999;

  • fAfra et al., 2008;

  • gZangaladze et al., 2008;

  • hGötz-Trabert et al., 2008;

  • iQuesney, 1986;

  • jSpencer et al., 1992;

  • kSpanedda et al., 1997;

  • lSpencer et al., 1987.