Neuron anatomy parameters for axon growth model
| Neurons | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| RB | dlc | dla | aIN | cIN | HdIN | RdIN | CdIN | mn | |
| Soma | |||||||||
| Number per side | 68 | 55 | 33 | 60 | 198 | 33 | 43 | 37 | 176 |
| DV (μm) | 135 | 123 | 123 | 85 (12) | 87 (17) | 56.2 (16) | 70 (17) | 71 (15) | 11.8 (5.7) |
| Axons | |||||||||
| Prim length (μm) | 905 (326) | 1071 (434) | 2018 (409) | 1002 (376) | 707 (319) | 893 (322) | 999 (298) | 821 (339) | 93 (79) |
| Sec length (μm) | 1227 (568) | 525 (344) | 487 (396) | 563 (400) | 464 (159) | 189 (98) | |||
| Initial angle (°) | 180 | −81 (23) | −143 (29) | −93 (31) | −86 (23) | −69 (11) | −69 (11) | −69 (11) | −45 |
| Prim tortuosity | 1.008 (0.006) | 1.017 (0.010) | 1.016 (0.017) | 1.019 (0.008) | 1.009 (0.013) | 1.015 (0.008) | 1.009 (0.008) | ||
| Sec tortuosity | 1.015 (0.011) | 1.021 (0.017) | 1.014 (0.016) | 1.056 (0.017) | 1.022 (0.014) | ||||
| Branch | |||||||||
| Angle (°) | 0 | 20 (23) | 39 (42) | 14 (17) | 180 | 180 | |||
| dist (μm) | 1 | 11 (8) | 70 (23) | 11 (14) | 1 | 100 (99) | |||
| Dendrites | |||||||||
| Dorsal extent | 120 | 120 | 54.1 (11.8) | 56.5 (17.8) | 70.7 (22.5) | 59.0 (12.0) | 60.7 (18.8) | 56.7 (6.4) | |
| Ventral extent | 100 (8.9) | 104.8 (8.5) | 6.9 (9.3) | 26.4 (11.2) | 19.0 (17.1) | 21.2 (18.2) | 31.1 (17.3) | 13.3 (3.5) | |
Measured values are expressed as means (SD). Values in italics were fixed in the model as follows: dorsoventral positions of somata of sensory RB neurons, and sensory pathway dla and dlc neurons so they lay in the strict longitudinal columns that they form in vivo; some initial and/or branch angles because there is negligible variation in vivo; axon branch positions of RB and HdIN (hindbrain descending interneuron) because all occur at the soma; soma numbers because all are based on current best estimates (Borisyuk et al., 2011). Prim and Sec are primary and secondary axons. Branch dist is the distance of an axon branch from the soma. Excitatory dINs were subdivided into three populations (Hindbrain, Rostral, and Caudal) because some features like initial axon outgrowth angle and possession of a secondary ascending axon change with longitudinal position.