Table 2.

Functional MRI responses to approaching and withdrawing faces and cars (n = 21)

RegionBAHemiTal (x, y, z)Size (mm2)Zp
A. Faces Approach versus Faces Withdrawal contrast
    Approach > Withdrawal
        Precuneus7R11, −44, 51291.15.63 × 10−8
7L−8, −44, 54155.54.82 × 10−6
        Superior parietal gyrus (dorsal)a7L−19, −70, 40553.75.31 × 10−7
7R10, −53, 57397.85.22 × 10−7
7R25, −51, 52191.24.32 × 10−5
7R35, −41, 5780.44.32 × 10−5
7L−17, −57, 5960.54.32 × 10−5
7/2R30, −33, 4414.63.91 × 10−4
7/5L−34, −44, 5687.13.91 × 10−4
7L−12, −52, 5620.03.72 × 10−4
7/5L−22, −47, 5715.63.72 × 10−4
7L−23, −51, 6117.03.63 × 10−4
        Mid-cingulate gyrus24L−14, −17, 4169.64.65 × 10−6
24R14, −13, 3854.64.23 × 10−5
24L−13, −16, 3512.13.55 × 10−4
        Precentral gyrus (dorsal); middle frontal gyrus4R37, −4, 44138.24.58 × 10−6
6R23, 5, 4414.03.91 × 10−4
6L−31, −1, 4154.23.72 × 10−4
        Superior parietal gyrus (ventral)7R20, −73, 3579.64.41 × 10−5
7R24, −69, 4133.54.32 × 10−5
        Precentral gyrus (ventral)b6L−51, −3, 2735.94.07 × 10−5
6L−55, −2, 3548.73.72 × 10−4
6R52, −3, 29108.63.72 × 10−4
        Middle occipital gyrus, inferior temporal gyrus18L−30, −87, 1550.84.07 × 10−5
37R45, −71, 764.84.07 × 10−5
19R40, −76, 2013.33.72 × 10−4
37L−40, −73, 423.23.72 × 10−4
    Withdrawal > Approach
        Inferior parietal gyrus, supramarginal gyrus40R45, −58, 4246.63.72 × 10−4
B. Faces Approach − Withdrawal versus Cars Approach − Withdrawal contrast
    Superior parietal gyrus (dorsal)a7R11, −53, 57202.04.73 × 10−6
7R35, −41, 5656.94.32 × 10−5
7R19, −58, 5126.14.23 × 10−5
7R30, −33, 4424.03.91 × 10−4
7R25, −51, 5214.83.72 × 10−4
    Precuneus7R12, −44, 55114.84.15 × 10−5
    Superior frontal gyrus6R22, 4, 4410.94.07 × 10−5
    Precentral gyrus (ventral)b6R54, −1, 2443.03.98 × 10−5
    Precentral gyrus (dorsal), middle frontal gyrus6R38, −4, 4546.83.99 × 10−5
    Superior parietal gyrus (ventral)7R24, −69, 4111.23.91 × 10−4
    Middle, inferior temporal gyri39R42, −64, 1124.93.72 × 10−4
    Postcentral gyrus43R61, −11, 2414.33.63 × 10−4

  • A, Clusters are listed which showed significantly (p < 0.05, FDR corrected, cluster size threshold >10 mm2) greater activation to Approaching versus Withdrawing face stimuli, as well as one cluster in the inferior parietal cortex showing greater activation to Withdrawing, compared with Approaching, faces (n = 21). B, Clusters are listed which showed a significantly greater approach bias (Approach > Withdrawal) to face compared to car stimuli (n = 21). No cluster showed a greater approach bias to cars compared with faces. Clusters falling within the predefined anatomical regions-of-interest (DIPS, PMv) are indicated with a and b (a, DIPS; b, PMv). Figs. 2, 3. Note that although the peak activations shown at the bottom are in the right hemisphere only, this is because the FDR threshold was higher for the left than for the right hemisphere (because of overall higher levels of activation in the right (vs the left hemisphere). At a non-FDR corrected threshold (p < 0.0005, cluster size >20 mm2), there is activation for this contrast in both the left (−18, −72, 43; z = 4.5; p = 7 × 10 −6; 88 mm2) and right (11, −53, 57; z = 4.7; p = 3 × 10 −6; 213 mm2) DIPS and left (−52, −3, 28; z = 4.4; p = 1 × 10−5; 97 mm2) and right (54, −1, 24; z = 3.9; p = 8 × 10−5; 47 mm2) PMv. BA, Brodmann area; Hemi, hemisphere; Tal, Talaraich coordinates of peak vertex; L, left; R, right.