Table 4.

NKCC1 genotype demographics from subjects recruited from the CBDB Sibling Studya

T/TA carriers
Total13491
Age (years)31 ± 932 ± 10
Gender57 M; 77 F43 M; 48 F
WAIS-IQ107.4 ± 9.8108.5 ± 8.5
Education (years)16.9 ± 2.517.1 ± 2.8
2-back accuracy (%)82.3 ± 15.681.0 ± 17.6
2-back reaction time (s)0.50 ± 0.230.52 ± 0.23
  • aFrom available healthy subjects with QC + fMRI data and NKCC1 rs3087889 genotypes (specific to the Δ21 transcript), there was a sample of 313 white healthy volunteers. Exclusion criteria included history of psychosis, head trauma, significant medical condition, or current psychiatric medications. The genotype groups were matched for age, gender, WAIS-IQ, N-back reaction time, and N-back performance (p > 0.05).