Table 3.

Total gray matter volume and hippocampal volume and microstructure of subjects before and after the intervention/control period

ParameterResveratrolPlacebo
PrePostpaPrePostpa
Total gray matter volume (cm3)576.2 ± 52.8575.3 ± 54.70.64568.6 ± 45.2566.7 ± 43.00.23
    HCant, left
        Volume (cm3)2.28 ± 0.352.26 ± 0.340.572.21 ± 0.282.21 ± 0.260.87
        MD (m2/s)1.17 ± 0.081.18 ± 0.070.501.15 ± 0.061.16 ± 0.080.30
    HCpost, left
        Volume (cm3)1.59 ± 0.251.58 ± 0.240.741.54 ± 0.211.56 ± 0.200.24
        MD (m2/s)1.08 ± 0.101.09 ± 0.090.711.09 ± 0.091.09 ± 0.110.50b
    HCant, right
        Volume (cm3)2.32 ± 0.262.29 ± 0.290.252.29 ± 0.192.33 ± 0.190.32
        MD (m2/s)1.11 ± 0.071.12 ± 0.070.431.13 ± 0.081.11 ± 0.090.41
    HCpost, right
        Volume (cm3)1.65 ± 0.211.63 ± 0.200.081.63 ± 0.171.63 ± 0.230.96
        MD (m2/s)1.05 ± 0.101.07 ± 0.080.581.05 ± 0.081.06 ± 0.110.62

  • Data are given as mean ± SD. Microstructure was measured using MD estimates.

  • ↵aPaired t test except

  • ↵bWilcoxon-signed-rank-test.