Table 2.

Mean (SD) annual percentage volume, area, and thickness change in the respective cortical regions

Cortical regionPercentage longitudinal annual cortical change
VolumeAreaThickness
Mean percentageSDMean percentageSDMean percentageSD
Cingulate
    Caudal anterior cingulate−0.59a(0.97)−0.24a(0.54)−0.39a(0.93)
    Rostral anterior cingulate−0.31a(1.04)−0.09(0.61)−0.32a(0.86)
    Posterior cingulate−0.71a(0.86)−0.37a(0.47)−0.41a(0.72)
    Retrosplenial cortex−0.53a(0.81)−0.17a(0.64)−0.35a(0.68)
Frontal
    Superior frontal−0.60a(0.82)−0.22a(0.36)−0.40a(0.76)
    Caudal middle frontal−0.71a(1.09)−0.30a(0.38)−0.46a(1.00)
    Rostral middle frontal−0.49a(1.00)−0.27a(0.39)−0.29a(0.89)
    Pars opercularis−0.51a(0.93)−0.52a(0.75)−0.58a(1.62)
    Pars triangularis−0.38a(1.06)−0.21a(0.44)−0.22a(0.97)
    Pars orbitalis−0.55a(0.93)−0.34a(0.66)−0.23a(0.85)
    Lateral orbital frontal−0.51a(0.79)−0.21a(0.41)−0.32a(0.80)
    Medial orbital frontal−0.63a(1.04)−0.18a(0.64)−0.48a(0.89)
    Frontal pole−0.30a(1.10)−0.12(1.37)−0.20(0.98)
Parietal
    Insula−0.32a(0.60)−0.15a(0.41)−0.26a(0.48)
    Precentral−0.49a(1.12)−0.07(0.41)−0.41a(1.14)
    Postcentral−0.47a(1.09)−0.07(0.35)−0.37a(1.09)
    Paracentral−0.52a(1.12)−0.12a(0.41)−0.36a(1.12)
    Superior parietal−0.61a(1.19)−0.17a(0.29)−0.40a(1.10)
    Inferior parietal−0.70a(0.95)−0.27a(0.29)−0.45a(0.86)
    Supramarginal−0.57a(0.93)−0.21a(0.28)−0.37a(0.84)
    Precuneus−0.64a(1.04)−0.21a(0.28)−0.45a(0.91)
Temporal
    Parahippocampal−0.59a(0.85)−0.31a(0.42)−0.32a(0.80)
    Entorhinal−0.34a(1.18)−0.24a(1.03)−0.19(0.87)
    Temporal pole−0.27a(0.79)−0.11(0.92)−0.20a(0.62)
    Superior temporal−0.46a(0.70)−0.12a(0.27)−0.39a(0.61)
    Middle temporal−0.60a(0.78)−0.24a(0.39)−0.42a(0.69)
    Inferior temporal−0.68a(0.79)−0.29a(0.40)−0.41a(0.69)
    Transverse temporal−0.56a(1.04)−0.40a(0.67)−0.25a(1.04)
    Banks sup temporal−0.64a(0.97)−0.30a(0.33)−0.46a(0.89)
    Fusiform−0.57a(0.83)−0.25a(0.39)−0.35a(0.73)
Occipital
    Lateral occipital−0.52a(0.93)−0.26a(0.43)−0.30a(0.81)
    Pericalcarine−0.04(1.37)−0.16a(0.51)−0.01(1.06)
    Lingual−0.54a(0.90)−0.34a(0.48)−0.28a(0.69)
    Cuneus−0.41a(1.15)−0.32a(0.51)−0.14(0.98)
  • ap < 0.05 (Bonferroni corrected, factor of 34).