Table 3.

Group differences in the left language tracts for all DTI metrics

Language left tractsDTI metrics
HCNfvPPApSvPPApLvPPAp
SLF II, III
    FA0.387 (0.018)0.341 (0.027)*0.0000.366 (0.032)0.120.373 (0.015)0.46
    MD0.596 (0.022)0.647 (0.031)*0.0010.623 (0.037)0.090.625 (0.030)0.06
    AD0.856 (0.024)0.886 (0.028)0.0460.871 (0.030)0.560.884 (0.036)0.09
    RD0.465 (0.022)0.528 (0.036)*0.0000.499 (0.042)0.080.493 (0.028)0.10
AF
    FA0.379 (0.017)0.324 (0.021)*0.0000.339 (0.033)*0.0000.353 (0.024)0.03
    MD0.600 (0.021)0.661 (0.028)*0.0000.646 (0.048)0.0060.648 (0.044)0.004
    AD0.865 (0.024)0.911 (0.028)0.0080.904 (0.049)0.050.917 (0.050)0.004
    RD0.470 (0.022)0.540 (0.030)*0.0000.519 (0.050)0.0040.516 (0.041)0.008
Anterior ILF
    FA0.221 (0.014)0.209 (0.022)0.370.182 (0.024)*,c0.0000.218 (0.020)0.98
    MD0.707 (0.019)0.727 (0.029)0.490.828 (0.038)*,a,c0.0000.735 (0.061)0.23
    AD0.880 (0.022)0.894 (0.028)0.740.974 (0.038)*,a,c0.0000.907 (0.058)0.23
    RD0.621 (0.020)0.646 (0.033)0.300.751 (0.038)*,a,c0.0000.648 (0.060)0.28
ILF
    FA0.383 (0.020)0.359 (0.016)0.060.352 (0.030)0.0120.360 (0.028)0.09
    MD0.643 (0.022)0.672 (0.018)0.050.694 (0.040)*0.0000.689 (0.034)*0.001
    AD0.922 (0.027)0.946 (0.019)0.340.989 (0.049)*0.0000.980 (0.051)*0.001
    RD0.496 (0.022)0.525 (0.021)0.070.541 (0.039)0.0030.539 (0.040)0.005
IFOF
    FA0.373 (0.016)0.349 (0.009)0.0100.336 (0.024)*0.0000.362 (0.023)0.46
    MD0.652 (0.022)0.690 (0.014)*0.0010.687 (0.026)0.0030.683 (0.028)0.009
    AD0.927 (0.026)0.961 (0.016)0.0040.948 (0.025)0.150.958 (0.025)0.014
    RD0.509 (0.023)0.546 (0.015)*0.0020.547 (0.029)0.0030.536 (0.034)0.05
UF
    FA0.314 (0.018)0.288 (0.020)0.050.264 (0.023)*,c0.0000.304 (0.026)0.65
    MD0.679 (0.023)0.718 (0.025)0.010.743 (0.033)*0.0000.704 (0.046)0.21
    AD0.931 (0.025)0.951 (0.026)0.260.963 (0.026)0.0350.944 (0.035)0.65
    RD0.556 (0.025)0.600 (0.028)0.010.634 (0.039)*,c0.0000.579 (0.052)0.40
  • MD, AD, and RD values are reported as mean (SD) in mm2/s × 10−3.

  • *Significant differences between PPA variants and healthy controls at p < 0.002 (Bonferroni adjusted).

  • an Significant differences from nonfluent variants at p < 0.05.

  • bn Significant differences from semantic variants at p < 0.05.

  • cn Significant differences from logopenic variants at p < 0.05.