Table 3.

Hand-sensitive activation in the sighted and blind subjectsa

Spatial extent test/cluster size (mm3)p valuesMNI coordinatesZ valueHemisphereAnatomical region
xyz
Overlap of hand-sensitive activation between vision and haptics in the sighted (conjunction analysis, Fig. 3C)
    19104<0.001−42−7644.6LMiddle occipital gyrus
−58−46−25.3LMiddle temporal gyrus
−64−4685.5LSuperior temporal gyrus
−56−40305.1LSupramarginal gyrus
−48−58165.6LAngular gyrus
−38−70−23.3LInferior occipital gyrus
    8224<0.00148−6604.0RMiddle occipital gyrus
60−5045.0RMiddle temporal gyrus
48−3863.5RSuperior temporal gyrus
48−60243.4RAngular gyrus
58−62−43.5RInferior temporal gyrus
    2016<0.00162−30284.4RSupramarginal gyrus
    2256<0.001−45484.0LSuperior frontal gyrus
452164.1RSuperior frontal gyrus
04243.0Cingulate gyrus
Hand-sensitive activation in the blind (both congenital and noncongenital, Fig. 3D)
    21408<0.001−48−78245.2LMiddle occipital gyrus
−60−5605.2LMiddle temporal gyrus
−52−56−63.6LInferior temporal gyrus
−60−50204.1LSuperior temporal gyrus
−46−74325.0LAngular gyrus
−60−38386.8LSupramarginal gyrus
    15896<0.00154−6843.8RMiddle occipital gyrus
60−5684.5RMiddle temporal gyrus
58−46103.9RSuperior temporal gyrus
44−52145.8RAngular gyrus
58−38465.1RSupramarginal gyrus
46−42584.4RSuperior parietal lobule
    4592<0.001−8−60343.4LPrecuneus
−12−54404.2LSuperior parietal lobule
−8−48325.0LCingulate gyrus
6−42264.7RCingulate gyrus
    2064<0.00152−12−283.4RInferior temporal gyrus
48−2−303.8RMiddle temporal gyrus
506−244.2RSuperior temporal gyrus
    1480<0.0148−40303.2RAngular gyrus
44−36404.0RSupramarginal gyrus
34−42424.0RSuperior parietal lobule
    1192<0.05846384.9RSuperior frontal gyrus
2440343.2RMiddle frontal gyrus
    7336<0.001−1240−64.7LSuperior frontal gyrus
648−24.1RSuperior frontal gyrus
−24004.1LCingulate gyrus
63683.8RCingulate gyrus
    2472<0.001−1226604.6LSuperior frontal gyrus
−2422543.3LMiddle frontal gyrus
    1032<0.05−466184.3LPrecentral gyrus
−5012104.2LInferior frontal gyrus
    1536<0.0122−86−425.1RCerebellum
    1360<0.0142−60−445.0RCerebellum
  • aThe activation was thresholded at p < 0.05, corrected for multiple comparisons over the whole brain, with the height threshold set at Z > 2.58. x, y, and z are stereotaxic coordinates (mm). R, Right; L, left.