Table 3.

Comparison of changes (%) in EPSP amplitude and PPR caused by hyperpolarization of the presynaptic mitral cells or by block of T-type channels with Z941 (10 μm)

Control (n = 8)Hyperpolarized (n = 8)% changePre-Z941 (n = 5)Z941 (n = 5)% change
EPSP1 (mV)0.76 ± 0.190.54 ± 0.15−28.9%1.28 ± 0.360.92 ± 0.27−28.1
p < 0.0001p = 0.0040
EPSP2 (mV)0.33 ± 0.050.32 ± 0.05−3.0%0.34 ± 0.080.37 ± 0.078.8
p = 0.6624p = 0.7510
PPR0.50 ± 0.070.70 ± 0.0740.0%0.35 ± 0.080.50 ± 0.0942.9
p = 0.0009p = 0.0032