Table 1.

Regions with a significant increase in fMRI signal for increasing prospective gains at the time of incentive presentation (p < 0.001, uncorrected)

Brain regionLateralityPeak Talairach coordinates (mm)Peak t value
Striatum (nucleus accumbens, ventral putamen)*R1214−116.43
Striatum (nucleus accumbens, ventral putamen)*L−158−115.99
Supplementary motor area*R92708.04
Parietal cortex*L−21−64587.29
Posterior cingulateR9−67135.37
Occipital cortexL−12−70105.93
Dorsolateral prefrontal cortexR3344314.76
Dorsolateral prefrontal cortexL−3338405.11
Anterior cingulateR911465.95
  • At the time of incentive presentation, no regions showed decreasing activity for increasing prospective gains. Statistically significant activations are those found in a priori regions of interest (familywise error, *p < 0.05) and those regions that survive whole-brain correction for multiple comparisons (at *p < 0.05). Laterality - right (R); left (L); central (C).