Table 1.

TDP-43 expression alters Futsch protein localization

D42>w1118 (absolute value; ratio to w1118 VG)D42>TDPWT (absolute value; ratio to w1118)D42>TDPG298S (absolute value; ratio to w1118)
VG1.20 ± 0.07; 1.01.96 ± 0.15; 1.63 (p = 0.01)1.94 ± 0.16; 1.61 (p = 0.01)
NMJ1.72 ± 0.09; 1.40.92 ± 0.04; 0.53 (p = 0.001)0.96 ± 0.06; 0.56 (p = 0.001)
  • Futsch protein levels normalized to actin at the ventral ganglia (VG) and NMJ. Genotypes are as indicated. Mean ± SEM and p values are as shown. See also Fig. 8. Western blots were performed as described in Materials and Methods.