Table 1.

Altered expression of Reelin signaling-associated genes in a VRK1 R358X mutant cell line

Gene symbolGlobal expression array fold changeaQuantitative real-time PCR fold change (±SD)b
APP−38.2*−333.4 (±52.3)*
PIK3CG−2.6**−2.3 (±0.3)**
CNR12.0**9.8 (±6.5)c
APBB12.1*77.3 (±36.5)*
FYN2.3*6.9 (±0.5)**
ARHGEF34.1*7.1 (±2.4)*

  • ↵aVRK1 R358X cell line versus mean of two different control cell lines.

  • ↵bVRK1 R358X cell line versus mean of three different control cell lines.

  • ↵cNot significant.

  • ↵*p < 0.05,

  • ↵**p < 0.001.