Table 1.

Proteins up-regulated in iPSCMNs compared with ESCMNs (with an expression ratio >2.00)

Protein IDProtein nameRatioGO term
G5E8H3DNA binding protein Ikaros5.37No hit
P09041Phosphoglycerate kinase 23.35Catalytic activity
Q6ZPI3Ligand dependent corepressor2.77Binding and catalytic activity
Q2TPA8Hydroxysteroid dehydrogenase like protein 22.75Catalytic activity
P52927High mobility group protein HMGI-C2.69Binding activity
Q6PAL8DENN domain-containing protein 5A2.51Transporter activity
Q9QUG2DNA polymerase kappa2.51Binding and catalytic activity
Q62470Integrin alpha 32.48No hit
F2Z4B7Protein Raph12.44No hit
Q60953Protein PML2.44No hit
E9PY58Caseinolytic peptidase B protein homolog2.41No hit
P70278Stimulated by retinoic acid gene 8 protein2.39No hit
E9Q9J4Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 22.34No hit
E9QN98Inactive dipeptidyl peptidase 102.29Catalytic activity
Q9CR58Kidney mitochondrial carrier protein 12.29Binding and transporter activity
Q8C0E3Tripartite motif containing protein 472.25No hit
Q9QUG9RAS guanyl-releasing protein 22.14Binding and catalytic activity and enzyme regulator activity
A2RT91Ankyrin and armadillo repeat-containing protein2.12No hit
F6TMC0Protein 9930021J03Rik2.12No hit
Q8K0F1TBC1 domain family member 232.12No hit
Q9ET80Junctophilin 12.10No hit
S4R2F7RNA binding protein 252.05No hit
E9PYH2Cytosolic acyl coenzyme A thioester hydrolase2.05No hit
Q3V3R4Integrin alpha-12.03No hit
P00405Cytochrome c oxidase subunit 22.03Catalytic activity
E9QP35Protein 2310042D19Rik2.03Catalytic activity
F7CHR4Inositol oxygenase2.03No hit
E9PXP1Protein Brpf12.01No hit
  • Ratio, Expression in iPSCMNs divided by the expression in ESCMNs; GO term, gene ontology assigned using Panther (www.pantherdb.org).