Demographic data and cognitive tests
| T/T carrier | G-allele carrier | Main group effect | Group × age interaction | |
|---|---|---|---|---|
| p value (uncorrected) | p value (uncorrected) | |||
| Demographic | ||||
| Number | 59 | 61 | N/A | N/A |
| Age (years) | 63.8 ± 7.0 | 63.2 ± 7.0 | 0.61 | N/A |
| Education (years) | 10.6 ± 3.2 | 10.1 ± 3.1 | 0.36 | N/A |
| Gender (male/female) | 26/33 | 24/37 | 0.60 | N/A |
| APOE-ϵ4 genotype (+/−) | 18/41 | 10/51 | 0.07 | N/A |
| Cognitive assessment | ||||
| General cognitive test | ||||
| MMSE | 26.4 ± 2.2 | 27.3 ± 1.8 | N/A | 0.01* |
| Specific cognitive test | ||||
| AVLT Delayed Recall | 3.2 ± 2.1 | 4.1 ± 2.7 | 0.06 | 0.65 |
| Clock Drawing Test | 24.1 ± 5.3 | 24.5 ± 3.7 | 0.55 | 0.61 |
| Category Fluency Test | 39.9 ± 10.0 | 42.5 ± 8.2 | 0.11 | 0.55 |
| Boston Naming Test | 22.0 ± 3.9 | 23.3 ± 3.6 | 0.03* | 0.59 |
| Symbol Digit Modifying Test | 30.7 ± 12.1 | 32.6 ± 10.9 | 0.30 | 0.84 |
| Trail Making Test A | 65.2 ± 30.7 | 63.6 ± 23.0 | 0.96 | 0.49 |
| Trail Making Test B | 219.4 ± 107.4 | 190.2 ± 76.2 | 0.07 | 0.81 |
| Stroop Color and Word Test C | 84.8 ± 36.2 | 78.5 ± 26.0 | 0.32 | 0.22 |
↵*p < 0.05 (uncorrected).