Table 1.

Distribution of sympathetic (PRV152) and sensory (H129) neurons across the neuroaxis

PRV152H129PRV152 + H129Percentage of PRV152 + H129
Hindbrain
    7N67.4 ± 12.157.6 ± 19.511.8 ± 3.010.4 ± 1.3
    10N16.0 ± 8.214.5 ± 1.22.0 ± 1.65.7 ± 4.7
    12N24.3 ± 5.217.0 ± 8.00.7 ± 0.31.9 ± 1.0
    PnO38.0 ± 16.027.4 ± 9.66.4 ± 2.511.3 ± 1.1
    PnC51.4 ± 15.142.6 ± 8.19.2 ± 2.510.6 ± 1.9
    SuVe74.2 ± 20.859.6 ± 16.113.2 ± 2.412.1 ± 1.8
    MPB36.6 ± 10.340.5 ± 8.47.6 ± 1.512.7 ± 1.1
    LPBI6.3 ± 2.95.3 ± 1.61.7 ± 0.87.3 ± 4.7
    LPBC23.6 ± 7.113.4 ± 5.33.0 ± 1.29.5 ± 4.3
    MPBE11.3 ± 5.611.3 ± 4.72.0 ± 0.78.0 ± 2.6
    LC29.8 ± 9.928.3 ± 5.75.0 ± 1.58.5 ± 2.4
    Bar16.3 ± 6.69.7 ± 4.63.8 ± 1.211.6 ± 4.8
    Pr529.0 ± 13.326.8 ± 9.65.5 ± 2.311.3 ± 0.8
    LDTg13.3 ± 4.64.3 ± 0.71.7 ± 0.712.3 ± 7.0
    Mo518.7 ± 3.320.7 ± 1.13.7 ± 0.510.2 ± 1.0
    RMg83.8 ± 25.987.2 ± 17.717.2 ± 4.111.4 ± 1.2
    RPa159.2 ± 34.0148.8 ± 41.636.2 ± 9.212.6 ± 1.1
    ROb154.5 ± 55.9116.0 ± 14.130.5 ± 5.012.9 ± 1.4
    Gi52.8 ± 28.839.0 ± 13.56.2 ± 3.06.4 ± 2.2
    LPGi31.0 ± 6.629.0 ± 6.87.0 ± 1.313.0 ± 1.2
    DPGi42.0 ± 17.342.3 ± 16.57.3 ± 2.88.5 ± 1.0
    GiV108.0 ± 19.7127.2 ± 32.419.0 ± 3.09.2 ± 1.0
    PCRt14.0 ± 4.110.7 ± 3.91.3 ± 0.54.6 ± 2.0
    IO152.7 ± 41.6129.3 ± 15.025.7 ± 6.19.8 ± 1.8
    LRt120.7 ± 36.196.0 ± 24.018.7 ± 2.99.4 ± 1.0
    MdV59.3 ± 39.943.0 ± 18.09.0 ± 5.96.8 ± 3.4
    NTS275.7 ± 60.4201.2 ± 58.933.4 ± 4.27.3 ± 1.4
    SolC28.3 ± 5.221.0 ± 4.75.2 ± 1.110.5 ± 2.1
    SolCe7.2 ± 2.85.3 ± 2.01.3 ± 0.49.3 ± 2.6
    SolDL31.8 ± 15.227.9 ± 14.84.7 ± 1.97.7 ± 1.7
    SolG21.7 ± 10.915.3 ± 4.52.8 ± 0.47.1 ± 2.3
    SolI7.4 ± 3.04.8 ± 1.51.2 ± 0.29.3 ± 3.1
    SolIM25.3 ± 8.819.5 ± 4.13.7 ± 1.37.9 ± 2.2
    SolM97.3 ± 12.066.0 ± 14.512.7 ± 4.37.2 ± 2.0
    SolV11.7 ± 3.410.8 ± 3.52.0 ± 0.28.6 ± 1.3
    SolVL45.8 ± 18.332.1 ± 10.26.0 ± 2.87.5 ± 2.4
    Pr25.5 ± 11.215.0 ± 6.63.8 ± 2.86.2 ± 3.1
Midbrain
    PAG260.6 ± 51.3109.2 ± 28.832.0 ± 5.89.6 ± 1.5
    DMPAG32.4 ± 9.312.2 ± 4.72.8 ± 1.116.3 ± 1.2
    DLPAG26.0 ± 6.18.4 ± 2.6*1.8 ± 0.75.1 ± 1.6
    LPAG60.0 ± 11.530.0 ± 6.9*8.8 ± 1.311.5 ± 2.1
    VLPAG54.8 ± 11.618.2 ± 6.06.4 ± 1.410.3 ± 1.8
    DR23.6 ± 6.77.0 ± 2.2*2.4 ± 0.67.7 ± 2.4
    DpMe54.3 ± 20.319.0 ± 6.46.0 ± 1.98.5 ± 3.1
    R18.0 ± 5.59.6 ± 2.92.6 ± 0.29.4 ± 3.3
    VTA32.5 ± 12.713.5 ± 4.63.5 ± 1.27.6 ± 2.8
Forebrain
    MPA79.8 ± 8.96.4 ± 3.0*2.2 ± 1.03.0 ± 1.7
    MPO36.4 ± 13.86.8 ± 2.6*1.4 ± 0.95.0 ± 3.0
    MnPO17.4 ± 5.20.8 ± 0.8*0.2 ± 0.22.0 ± 2.0
    LPO23.8 ± 10.51.5 ± 0.80.8 ± 0.41.7 ± 1.0
    AVPO32.6 ± 9.57.8 ± 5.91.4 ± 1.02.8 ± 1.7
    AVPe23.5 ± 7.93.3 ± 1.81.3 ± 0.83.3 ± 2.3
    SCh13.5 ± 6.94.5 ± 1.70.5 ± 0.41.2 ± 1.0
    AHA7.4 ± 2.23.8 ± 2.21 ± 0.49.2 ± 4.3
    AHP22.8 ± 9.19.8 ± 5.52.4 ± 1.35.8 ± 2.4
    PVH277.4 ± 55.5237.8 ± 58.748.8 ± 8.711.2 ± 1.8
    PaAP15.0 ± 4.914.8 ± 7.23.5 ± 1.710.7 ± 3.2
    PaDC30.6 ± 7.336.4 ± 11.36.2 ± 1.78.9 ± 3.1
    PaMP137.8 ± 22.1129.8 ± 32.823.6 ± 4.210.4 ± 1.7
    PaMM12.2 ± 4.97.2 ± 2.31.8 ± 1.16.8 ± 4.5
    PaLM36.0 ± 6.835.3 ± 10.75.8 ± 1.78.5 ± 1.4
    PaV16.7 ± 2.516.3 ± 4.23.3 ± 1.412.6 ± 5.8
    PaPo22.7 ± 12.025.4 ± 12.57.6 ± 5.28.4 ± 2.3
    Arc19.6 ± 7.18.2 ± 2.12.0 ± 0.95.9 ± 2.6
    LH101.6 ± 20.840.0 ± 3.911.8 ± 1.79.3 ± 0.6
    VMH6.4 ± 4.1000
    DM83.3 ± 31.830.3 ± 5.88.7 ± 1.79.8 ± 2.3
    PH39.8 ± 12.915.8 ± 1.55.0 ± 1.111.1 ± 1.5
    ZI18 ± 11.08.6 ± 4.51.2 ± 0.82.6 ± 1.7
    SubZI31.6 ± 4.622.4 ± 8.96.8 ± 2.013.5 ± 3.9
  • 7N, Facial nucleus; 10N, dorsal motor nucleus of the vagus nerve; 12N, hypoglossal nucleus; Arc, arcuate nucleus; AVPe, anteroventral periventricular nucleus; AVPO, anteroventral preoptic nucleus; Bar, Barrington's nucleus; GiV, gigantocellular reticular nucleus, ventral part; IO, inferior olive; LC, locus coeruleus; LDTg, laterodorsal tegmental nucleus; LPBC, lateral parabrachial nucleus, central part; LPBI, lateral parabrachial nucleus, internal part; LRt, lateral reticular nucleus; MdV, medullary reticular nucleus, ventral part; MnPO, median preoptic nucleus; Mo5, motor trigeminal nucleus; MPBE, medial parabrachial nucleus external part; PaAP, paraventricular hypothalamic nucleus, anterior parvicellular part; PaDC, paraventricular hypothalamic nucleus, dorsal cap; PaLM, paraventricular hypothalamic nucleus, lateral magnocellular part; PaMM, paraventricular hypothalamic nucleus, medial magnocellular part; PaPo, paraventricular hypothalamic nucleus, posterior part; PaV, paraventricular hypothalamic nucleus, ventral part; PCRt, parvicellular reticular nucleus; PH, posterior hypothalamic area; PnC, pontine reticular nucleus, caudal part; PnO, pontine reticular nucleus, oral part; Pr, prepositus nucleus; Pr5, principal sensory trigeminal nucleus; R, red nucleus; RMg, raphe magnus nucleus; SCh, suprachiasmatic nucleus; SolC, nucleus of the solitary tract, commissural part; SolM, nucleus of the solitary tract, medial part; SolVL, nucleus of the solitary tract, ventrolateral part.

  • Data are expressed as mean ± SEM (n = 5);

  • *p < 0.05 versus PRV152.