Table 1.

SPM results for the differences between placebo (PL) and alcohol (ALC)a

RegionBAMNI coordinates, mmPL > ALC (NS)PL > ALC (VS)
xyzHDNMLHDNML
Calcarine17−8−8207.23.75.62.3
Calcarine1712−7067.03.44.92.2
Cerebellum−40−64−406.83.84.12.6
Cerebellum−22−78−366.63.44.02.9
Vermis6−70−366.63.14.22.4
Superior occipital18−20−90226.33.04.1NSb
Cerebellum36−72−226.13.85.32.2
Fusiform3730−54−186.13.34.82.7
Middle occipital19−40−8406.03.14.41.9
Inferior frontal44−4810245.72.53.91.6
Superior orbitofrontal11−1838−225.62.54.12.2
Middle frontal47−384605.42.23.31.8
Inferior temporal20−52−10−265.32.13.8NSb
Inferior temporal2064−44−145.33.03.72.2
Middle cingulum232−38345.22.73.51.7
Middle occipital3948−74245.22.63.71.9
Middle orbitofrontal113042−165.22.84.62.0
Inferior frontal45523045.22.63.42.0
Superior temporal41−42−2885.12.04.3NSb
Supramarginal42−58−24185.11.73.3NSb
Superior frontal10−245825.12.03.31.7
Angular738−74405.12.83.52.4
Inferior frontal65610105.12.62.92.1
Superior frontal102456145.12.43.21.9
Angular39−50−62245.12.13.81.7
Superior temporal2252−2485.12.63.61.9
Inferior temporal2058−30−245.13.13.52.5
Precentral44486345.02.73.72.0
Superior temporal42−54−42185.02.23.2NSb
Middle frontal9−3040365.0NS2.5NSb
Inferior parietal3−52−26504.71.92.4NSb
Precentral6−362564.72.03.0NSb
Middle cingulum32836304.52.02.6NSb
Middle frontal8−2412564.41.92.9NSb
Precentral638−8564.31.72.6NSb
Thalamus014−1884.3NS2.7NSb
  • aData represent statistical significance (t-score) and the spatial location of the clusters showing significant differences in absolute glucose metabolism between placebo (PL) and alcohol (ALC) conditions under VS and NS for HDs and NMLs.

  • bNS, Not significant.