Table 1.

Animals used in this study

ExperimentStrain of residentIntruderDrugTotal animals used for analysisExcluded
1 Intra-DRN baclofen5-HTT− GABAB1−/− cKO (C57BL/6J background)C57BL/6JBaclofen (0.6, 0.3 nmol) or aCSF11 WT and 12 cKO8 missed placement, 3 stop fight, 2 dead
2 Glutamate and GABA microdialysis in the DRN during baclofen administrationICRBaclofen (0.6 nmol) or aCSF94 missed placement
3 Intra-DRN l-glutamateICRICRL-glutamate (0.1, 1 μm) or aCSF101 stop fight
4 Antagonism of l-glutamate by APV + NBQXICRICR1 μm L-glutamate with/without 50 μm APV + 10 μm NBQX, or saline113 stop fight, 6 missed placement
5 Glutamate microdialysis in the DRN during aggressive encounterICRICR113 missed placement, 2 broken probe, 1 stop fight, 1 sick
6 Glutamate microdialysis in the DRN during instigation-heightened aggressionICRICR101 missed placement, 1 stop fight, 3 mechanical problem
7 5-HT microdialysis in the DRN during aggressive encounterICRICR113 missed placement
8 5-HT microdialysis in the DRN during instigation-heightened aggressionICRICR111 missed placement
9 5-HT microdialysis in the mPFC during aggressive encounter and instigation-heightened aggressionICRICR9 (1 animal without-instigation only)1 damaged brain, 1 mechanical problem