Comparison of kinetic parameters derived from the whole-brain two-compartment analysis
| Kinetic parameter | Supine (n = 9) | Prone (n = 6*) | RLD (n = 8) | p-value |
|---|---|---|---|---|
| Retention = (k3/k4) | 10.70 (9.88, 12.50) | 14.98 (12.23, 16.53) | 6.86 (6.28, 9.47) | 0.008 |
| Loss = k2/(1 + k3/k4) | 0.23 (0.13, 0.26) | 0.14 (0.09, 0.21) | 0.31 (0.23, 0.40) | 0.021 |
Data are presented as median (1st quartile, 3rd quartile) for each group.
↵*One rat in the prone group was excluded from analysis due to two-compartmental fitting failure of the whole-brain TSCs for unknown reasons.