Table 1.

Freezing behavior following footshock and during fear recall in WT and PTH2R-KO male mice

Post shockPost recall
Freezing in recall test 28 d after shock
    WT
        ControlN/A0.10% ± 0.08
        ShockN/A9.63% ± 1.89
    PTH2R-KO
        ControlN/A0.01% ± 0.01
        ShockN/A16.42% ± 2.24*
Freezing 60 s after shock
    WT
        Control0.00% ± 0.000.00% ± 0.00
        Shock2.07% ± 0.580.26% ± 0.18
    PTH2R-KO
        Control0.02% ± 0.020.00% ± 0.00
        Shock0.82% ± 0.370.42% ± 0.17
  • Percentage of time spent freezing in the shock context during fear recall testing 28 d after shock or 60 s after receiving a shock. Nonshocked (control) and shocked WT and PTH2R-KO mice were from postshock and postrecall groups used for the evaluation of c-Fos expression.

  • *p < 0.05 versus shocked WT at the same time point. N/A, not available.