Table 5.

Description of control cases used for staining and expression analysisa

Control caseAge (yr)/sexCause of deathAutopsy intervalhR23A cytoplasm patternhR23A nucleus patternhR23B cytoplasm patternhR23B nucleus pattern
23 (Control Case 2 in Fig. 8)77/MCardiac failure6 hDiffuseLight stainingAbsentAbsent
2649/MCancer and obesity4 hDiffuseAbsentSome reticular with weak depositsAbsent
3167/MLung cancer3.5 hDepositsAbsentWeak depositsAbsent
3757/MCardiac arrest due to ventricular fibrillation14 hDepositsSome light nuclear stainingDiffuse throughout and scatteredAbsent
4261/MBrain tumor6 hScattered throughout cytoplasmLight stainingDepositsLight staining
4480/FLiver failure5 hSome weak depositsLight stainingReticularAbsent
6582/MUnknown4 hReticularPresentDiffuse and reticularAbsent
6777/MUnknown4 hReticularPresentDepositsStrong staining
78 (Control Case 1 in Fig. 8)58/FVasculitis, cerebral hemorrhage, hepatitis C3 hReticularAbsentReticularAbsent
  • aThe 9 control cases from which postmortem spinal cord tissue was taken following autopsy. Control Case 1 in Figure 12A was 78 and Control Case 2 in Figure 12A was 23. Control cases in Figure 12C were loaded in Western blot in this order: 6, 23, 67, 31, 26.