Table 2.

Methionine metabolite concentrations in MS and control cortical gray matter tissue

Homocysteine (nmol/g)SAM (nmol/g)SAH (nmol/g)Methionine (nmol/g)Cystathionine (nmol/g)Betaine (nmol/g)Choline (nmol/g)
MS (n = 30)12.3 (±6.1)12.5* (±3.7)15.6 (±4.9)88.7 (±44.8)525* (±469)47.8* (±30.8)232 (±115)
Control (n = 20)13.2 (±7.0)15.5 (±6.4) p = 0.0417.0 (±4.0)99.9 (±59.3)1389 (±1054) p = 0.000285.5 (±48.0) p = 0.001247 (±159)
  • The asterisks denote significance between MS and control concentrations (p < 0.05).