Table 2.

Two-way ANOVA of the data shown in Figure 2 (NTX and 6β-naltrexol)

RowFigureExperimentnVariable 1Variable 2InteractionSubject matching
12ACFA6Time (CFA)Sidep < 0.0001p = 0.001
p < 0.0001p = 0.0096F(9,90) = 7.8F(10,90) = 7.88
F(9,90) = 8.98F(1,10) = 10.21
22BCFA (NTX)6Time (NTX)Sidep = 0.15p < 0.0001
p < 0.0001p = 0.25F(6,60) = 1.6F(10,60) = 6.45
F(6,60) = 40F(1,10) = 1.5
32CCFA (6β-naltrexol)6Time (6β-naltrexol)Sidep = 0.89p < 0.0001
p = 0063p = 0.24F(6,60) = 0.38F(10,60) = 5.68
F(9,90) = 3.37F(1,10) = 1.5
42DCFA (NTX + 6β-naltrexol)6Time (NTX + 6β-naltrexol)Sidep = 0.999p < 0.0001
p = 0.42p = 0.81F(6,60) = 0.04F(10,60) = 14.6
F(9,90) = 1.02F(1,10) = 0.06
52ESaline8Time (saline)Sidep = 0.50p < 0.0001
p = 0.066p = 0.97F(7,98) = 0.91F(14,98) = 10.3
F(7,98) = 1.97F(1,14) = 0.002
62FSaline (NTX)8Time (NTX)Sidep = 0.95p < 0.0001
p = 0.87p = 0.29F(6,84) = 0.28F(14,84) = 7.08
F(6,84) = 0.42F(1,14) = 1.2
  • Each panel in Figure 2 (indicated in the second column) was analyzed independently by two-way ANOVA. In the fourth column, n is the number of animals in the experiment. In the fifth and sixth columns, the variable is identified first: “time” refers to the time after the injection of the compound in parentheses; “side” is ipsilateral versus contralateral paw. Subscript numbers in the F ratio are the degrees of freedom and the residual.