Table 4.

Two-way ANOVA of the data shown in Figure 5 (nor-BNI and JDTic)

RowFigureExperimentnVariable 1Variable 2InteractionSubject matching
15ARats CFA5Time (CFA)Sidep < 0.0001p < 0.0001
p < 0.0001p = 0.092F(7,56) = 5.7F(8,56) = 16.59
F(7,56) = 10.56F(1,8) = 4.23
25BRats CFA, nor-BNI 1.3 nmol (12 h)5Time (nor-BNI)Sidep = 0.95p < 0.0001
p < 0.0001p = 0.16F(4,32) = 0.18F(8,32) = 7.26
F(4,32) = 14.66F(1,8) = 2.42
35CSaline8Time (saline)Sidep = 0.96p < 0.0001
p = 0.46p = 0.42F(7,98) = 0.26F(14,98) = 3.82
F(7,98) = 0.96F(1,14) = 0.69
45DSaline (nor-BNI)8Time (nor-BNI)Sidep = 0.37p < 0.0001
p = 0.073p = 0.88F(4,56) = 1.1F(14,56) = 4.42
F(4,56) = 2.27F(1,14) = 0.025
55EMice CFA / saline6/6Time (CFA)CFAp < 0.0001p = 0.011
p < 0.0001p = 0.021F(6,60) = 11.2F(10,60) = 2.60
F(6,60) = 15.09F(1,10) = 7.48
65FMice CFA / saline, JDTic6/6Time (JDTic)CFAp < 0.0001p < 0.0001
p < 0.0001p = 0.0001F(4,40) = 15.3F(10,40) = 5.67
F(4,40) = 16.08F(1,10) = 36.03
• Each panel in Figure 5 (indicated in the second column) was analyzed independently by two-way ANOVA. In the fourth column, n is the number of animals in the experiment. In the fifth and sixth columns, the variable is identified first: “time” refers to the time after the injection of the compound in parentheses; “side” is ipsilateral versus contralateral paw, and “CFA” refers to CFA versus saline. Subscript numbers in the F ratio are the degrees of freedom and the residual.