Table 4.

Brain regions showing differential hippocampal connectivity during aversive learning

RegionVoxels (n)tTalairach coordinates
xyz
Main effect of task condition: CS+> CS−
    vmPFC823.25−1355
    Ventral striatum562.96−15−7
    Posterior insula393.9144−1611
Group × task condition: PI > comparisons × CS+ > CS−
    Right superior frontal gyrus, dmPFC4834.46201762
    Left middle frontal gyrus873.78−252356
    Corpus callosum, thalamus753.202−1620
    Posterior cingulate cortex603.792−2844
    vmPFC443.042535
    Precuneus443.75−1−7341
Age × task condition: age predicts decreased connectivity for CS+ > CS−
    vmPFC833.62−150−4
Age × task condition: age predicts increased connectivity for CS+ > CS×
    Precentral gyrus583.322568
    Central sulcus523.19−4−1371
    Cerebellum493.8526−37−49
Group × task condition × agea
  • aNo regions identified.