Table 1.

Survival data of 145 animals

Animals (n)	MCAo length (min)	TAT.application: Time/dose	TAT.β-Gal–sham: n/death event (day)	TAT.β-Gal–MCAo: n/death event (day)	TAT.ARC–sham: n/death event (day)	TAT.ARC–MCAo: n/death event (day)	Number of animals at survival endpoint	Data shown
24	60	During MCAo [1 μg]	—	12/1 (1);	—	12/0 (n/a)	23/3 d	Figs. 2, 3, 5, 6
30	60	3 h post MCAo [5 μg]	—	15/0 (n/a)	—	15/1^{^a} (1)	29/3 d	Fig. 7
40	60	During MCAo [1 μg]	5/0 (n/a)	15/0 (n/a)	5/0 (n/a)	15/0 (n/a)	40/3–24 h	Figs. 4, 6
5	n/a	TAT.ARCL31F/G69R	—	—	5/0 (n/a)	—	5/24 h	Fig. 6
46	30	3 h post MCAo [5 μg]	8/0 (n/a)	15/1 (7)	8/0 (n/a)	15/4 (1, 7, 8, 10)	41/28 d^{^b}	Fig. 8

↵^aSurvival was tested with the log-rank Mantel–Cox test with χ² = 6.081 (df = 3) and p = 0.11 indicative that survival did not differ between groups in the last experiment.
↵^bAnimal died after MCAo before TAT.application.